If migraine attacks are severe or frequent enough, medication may be required on a regular basis to prevent migraine. The four most commonly used medication groups are tricyclics, beta-blockers, calcium channel blockers, and some anti-seizure medications. Botox (botulinum toxin) injections also are sometimes used to treat chronic migraine, with multiple injections around the head and neck given over a period of weeks to help dull future headache symptoms. Your ophthalmologist (Eye M.D.) may provide migraine treatment, or may refer you to a neurologist or another specialist for further tests and evaluation.